3 03 gut bacteria obesity depression anxiety

We all carry trillions of bacteria in our guts, with as many as a thousand different strains. The composition of these strains, or our “bacterial fingerprint,” can influence whether we are prone to depression, anxiety, obesity, or Hashimoto’s hypothyroidism. “Bad” gut bacteria has been associated with low thyroid function and autoimmune Hashimoto’s. 

Some gut bacteria can make you fat

Studies have shown people (and mice) who are overweight have much higher levels of particular strains of bacteria than thinner subjects. When thin mice are inoculated with bacteria from heavy mice, they gain weight. This is because these fat-promoting bacteria have been shown to encourage overeating, promote weight gain, prevent the burning of fat, and make obese people better at deriving calories from food than thin people.

In a nutshell, your “bacterial fingerprint” plays a role in how much fat you carry and how easy or difficult it is for you to lose weight. Although diet and exercise are important, these findings help to explain why solely relying on the “eat less and exercise more” approach to weight loss is outdated.

Effect of gut bacteria on depression and anxiety

The composition of your gut bacteria can also play a role in whether you suffer from depression and anxiety. For instance, having plenty of beneficial bacteria, such as the Bifidobacteria strain, can promote production of serotonin, the “feel-good” chemical that prevents depression.

On the other hand, too much of “bad” bacterial strains can promote depression and anxiety. This is because the gut is linked to the brain by the vagus nerve, a large nerve that sends messages back and forth between the brain and digestive system. The effects of harmful bacteria in the gut travel to the brain, impacting brain function and mood.

In one study, subjects who took probiotics containing Lactobacillus and Bifidobacterium reported less anxiety, depression, and anger and an improved ability to solve problems. In another study, mice given a Lactobacillus strain cruised through a maze that normally created high anxiety and showed lower levels of the stress hormone cortisol compared to their probiotic-deprived counterparts.

Gut bacteria and Hashimoto’s hypothyroidism

Gut bacteria influence Hashimoto’s hypothyroidism in several ways. For one, certain strains of bacteria have been associated with triggering Hashimoto’s, an autoimmune disease in which the immune system attacks the thyroid gland. An overgrowth of bad bacteria can also promote Hashimoto’s hypothyroidism by promoting intestinal permeability, or leaky gut. This is a condition in which the gut wall becomes inflamed and porous, allowing inflammatory compounds into the bloodstream. Also, 20 percent of thyroid hormone is converted by intestinal bacteria to a form the body can use. A poor balance of bacteria can hinder this conversion.

Cultivating good gut bacteria

Although researchers are still unsure exactly how to banish obesity, depression, and anxiety with probiotics, it’s clear you need to enhance your bacterial fingerprint for optimal health.

Birthing and baby feeding affect gut bacteria

The balance of good and bad bacteria starts at birth—vaginal deliveries and breastfeeding have been shown to improve a child’s chances of starting off with a healthy bacterial colony compared to C-sections and bottle feeding.

Chronic stress and gut bacteria

Chronic stress can throw your bacterial harmony out of balance, as can diets filled with sweets and sugars, processed foods, and fast foods. These foods damage and inflame the intestinal walls, promoting overgrowth of bad bacteria and yeasts.

Cultured food and fiber promotes good gut bacteria

You can promote bacterial harmony by focusing on an anti-inflammatory, whole foods diet that includes cultured and fermented foods, such as kefir, sauerkraut, kimchi, and fermented vegetables. If you use store-bought cultured foods, make sure they are the real deal and not simply made with vinegar, or pasteurized, which would kill good bacteria..

A healthy colony of good gut bacteria also relies on plenty of soluble fiber in the diet. Eating plenty of produce will give you just what you need in that respect.

Probiotics for obesity, depression, and anxiety

Fortunately, we have powerful probiotics today that can help you cultivate your inner garden. Probiotics should be stable enough to survive the hot and acidic environment of the stomach and contain ample amounts of beneficial strains. Ask my office for advice on a probiotic that’s right for you.

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brain on fire

Do you suffer from brain fog — that spacey, detached feeling like your head is in a fish bowl? Do you suffer from depression, or does your child have autism? Are you concerned about Alzheimer’s? These conditions are signs of possible brain inflammation, or a brain “on fire.”

Although a head injury or infection are commonly associated with severe cases of brain inflammation, many people suffer from milder but chronic brain inflammation, which is linked to a variety of symptoms such as brain fog, depression, autism, or Alzheimer’s.

Hashimoto’s hypothyroidism is a risk factor for brain inflammation. Because it is an autoimmune disease, it can drive inflammation in the brain. Hypothyroidism may also contribute to brain inflammation by depriving the brain of sufficient thyroid hormone.

Brain inflammation and brain fog

Unlike most of the body, the brain does not produce pain when inflamed. Instead, one of the most common symptoms is brain fog, which makes people feel spaced out and disconnected. As Datis Kharrazian, DHSc, DC, MS explains in his book Why Isn’t My Brain Working?, this is because brain inflammation slows down the conduction between neurons. As a result, brain function slows, which causes that slowness and dullness of thinking.

Brain fog is a common symptom of Hashimoto’s hypothyroidism.

Brain inflammation and depression

Studies also show depression is linked with brain inflammation. Inflammation creates immune proteins called cytokines. These cytokines can impair brain function and the brain chemical serotonin; low serotonin is frequently linked with depression. In fact, up to a third of patients with hepatitis C who are given interferon, which increases cytokine activity, develop depression, mania, and hypomania.

Brain inflammation, autism, and ADHD

Brain inflammation has also been linked with autism and other brain development disorders in children. Patients with autism have more inflammatory disorders than average (such as digestive disorders, allergies, ear infections, or skin eruptions) and brain imaging and autopsies show more brain inflammation in individuals of all ages with autism.

Brain inflammation and Alzheimer’s

Research also links brain inflammation with Alzheimer’s. Although tau proteins and amyloid beta have long been the hallmarks of Alzheimer’s, studies increasingly show inflammation plays a large role in the disease. Not only does inflammation degenerate brain tissue, it also appears to increase amyloid beta, which in turn increases inflammation in a vicious cycle that chews up brain tissue.

Manage Hashimoto’s hypothyroidism to quench brain inflammation 

So what can be done about brain inflammation to protect brain function? In his brain book, Dr. Kharrazian outlines a number of approaches:

  • Manage Hashimoto’s hypothyroidism. Hashimoto’s is an autoimmune disease in which the immune system attacks the thyroid gland. The constant inflammation caused by an autoimmune condition can inflame the brain. Likewise, depriving the brain of sufficient thyroid hormone can lead to brain inflammation.
     
  • Nutritional therapy. Several natural compounds have been shown to quench brain inflammation—ask my office for more information.
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  • Keep blood sugar stable. Eating a whole foods diet that does not cause surges or drops in blood sugar is also important. Insulin resistance (high blood sugar), hypoglycemia (low blood sugar), and diabetes can all increase brain inflammation.
     
  • Food intolerances. It’s important to remove foods that trigger inflammation from your diet. For example, many people have intolerances to gluten grains, dairy, or other foods.
     
  • Balance hormones. Balanced hormones are also important to keep brain inflammation in check. For instance, low estrogen in women, low testosterone in men, or low thyroid hormones can play a role in brain inflammation.
     
  • Glutathione. Sufficient glutathione, the body’s master antioxidant, is also necessary to prevent brain inflammation, as are sufficient essential fatty acids and vitamin D.
     
  • Gut health. Also vitally important is to address gut inflammation. There is direct communication between the gut and the brain and gut inflammation has been shown to cause brain inflammation.

Ask my office for more information on how to manage brain inflammation for better brain and body health.

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